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Food and Drug Administration (FDA) updated the Ozempic label to include information about an increased risk of ileus, a condition that obstructs the passage of food or fluid through the intestines

[DOI] [PubMed] [Google Scholar] 26.Garvey WT, Frias JP, Jastreboff AM, le Roux CW, Sattar N, Aizenberg D, Mao H, Zhang S, Ahmad NN, Bunck MC, Benabbad I, Zhang XM SURMOUNT-2 investigators

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The difference, which was statistically significant, amounted to a 52% increased risk of being diagnosed with stomach paralysis while on a GLP-1 medication

Additionally, the pain or discomfort during defecation might result in incomplete evacuation, further contributing to constipation