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Vinegoni C
In vitro studies showed that exendin-4 is more potent than GLP-1 in producing GLP-1R desensitization
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Although comparison studies with GLP-1 RA's have been conducted in the past, new doses have since been approved, making it difficult to compare tirzepatide to GLP-1 RA's based on previous studies
Although conventional hypoglycemic agents effectively control blood glucose levels, they inadequately prevent major adverse cardiovascular events, such as myocardial infarction and stroke
Handb Exp Pharmacol, 255:109-120
