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Women with severe vasomotor symptoms should be treated with hormone therapy at the lowest dose possible per guidelines, and tirzepatide should remain top-of-the-list for weight loss in persons with obesity or overweight with comorbid illness, Uzmann says

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Baseline B12 assessment should be considered, particularly if you are taking metformin, following a plant-based diet, have had previous bariatric surgery, or have malabsorption conditions