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Common side effects include nausea, constipation, and mild fatigue during dose escalation, typically resolving within 12 weeks

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Doctors may prescribe Mounjaro off-label for weight loss, emphasizing the need for a thorough health evaluation

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Moreover, mitochondrial damage, increased oxidative stress, and endoplasmic reticulum stress are also involved in the development of IR [50]

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The therapeutic approach to target the incretin system for the treatment of type 2 diabetes involves the use of GLP-1 agonists or DPP-4 inhibitors to increase the levels of endogenous GLP-1 ( In addition to pancreatic localization, GLP-1R has been found in the gastrointestinal system, kidneys, central nervous system, and cardiovascular system (Pyke et al., 2014)

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There are several types of problematic sweating that can be related to diabetes

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Tirzepatid Tirzepatid, GLP-1 etkisine ek olarak GIP reseptr mekanizmasyla da ilikilendirilen ift etkili bir etken maddedir

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