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Canadian network for mood and anxiety treatments (CANMAT) 2023 update on clinical guidelines for management of major depressive disorder in adults: rseau canadien pour les traitements de lhumeur et de lanxit (CANMAT) 2023: Mise jour des lignes directrices cliniques pour la prise en charge du trouble dpressif majeur chez les adultes

One such additional indication is the treatment of substance use disorder

[00:06:14] Emily Field: In the major clinical trials for Glide and Tirzepatide participants experienced average weight losses in the range of 15 to 22% of body weight, which is quite significant compared to traditional lifestyle interventions alone

The FDA requires stopping these medications at least two months before attempting conception, based on animal reproduction studies showing possible developmental risks

Medications like Pepto-Bismol (bismuth subsalicylate) or Imodium (loperamide) can be used short term under your providers direction

Currently, no existing guidelines provide definitive directions on this clinical issue