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This in vivo data clearly indicates that our single-administration semaglutide PSR-MNs offers a similar effect to that provided by the use of multiple bolus injections

You may notice the benefits, such as appetite control or low blood sugar levels, fading gradually
Patients on metformin and another antihyperglycemic agent (N=229) and patients not on any antihyperglycemic agents (off therapy for at least 8 weeks, N=41) were randomized after a run-in period of approximately 10 weeks on metformin (at a dose of at least 1500 mg per day) in monotherapy

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