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To determine the optimal length of the linker between the peptide sequence and the PDGFR transmembrane anchor we first infected HEK293-GLP-1R-GFP cells with lentivirus encoding membrane-tethered Ex4 containing one, two or three repeats of the GlyGlyGlyGlySer linker sequence (Fig

With consistent exercise and a healthy diet, the drug also addresses weight gain in obese individuals

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The fate of taspoglutide, a weekly GLP-1 receptor agonist, versus twice-daily exenatide for type 2 diabetes

Jiang W, Wang Q, Zhang X, Yang H, Yang X

But the glucose-lowering effects of GLP-1 are glucose dependent