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Despite the promising results, the researchers caution that the study does not prove that GLP-1 medications directly prevent addiction or substance misuse

It has been proven that pancreatic islets have circadian genes such as CLOCK and BMAL1 in Homo sapiens and rodents (119, 120), and disruption of circadian genes leads to diabetes (121)

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Firstly, we noted a change in clinical practice over the time of the trial, with a general preference for a LSG or RYGB procedure compared to LAGB, especially in participants with T2DM