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However, in a subsequent cohort of diabetic patients treated for 5 weeks with liraglutide, activation of the OFC in response to food cues was increased, despite successful weight loss, improved metabolic profile, and reduced fat intake [36]

Key contributing factors include advancing age, long-standing disease duration, and suboptimal glycemic control, as well as insulin resistance and androgen deficiencythe latter being particularly common in men with type 2 diabetes (T2D) and obesity

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