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One study found that people with RA who started GLP-1 or SGLT2 medicine had fewer flares after starting treatment

GLP-1 RAs promote weight loss [41], hence our findings of an increase in weight with GLP-1 RA therapy at 5 years was interesting

13 In a third case, a 50-year-old female patient with obesity and T2DM was started on semaglutide (0.25mg per week x 4 weeks, then 0.5mg per week x 12 weeks, maintained on 1mg per week) and evaluated for changes in adipose tissue depots surrounding the heart and coronary arteries

doi: 10.1159/000517849

Young adults (aged 1834) were more likely to drop out of treatment sooner, and more than 30% of all patients dropped out after just four weeks, before reaching the targeted dose

These long-acting incretin receptor agonists have revolutionized the landscape of obesity and T2D research and are now being explored for other metabolic disorders, including non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD) [1]
