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Description
GLP-1 receptor agonists like semaglutide have shown protective effects on kidney function in multiple clinical trials, particularly for people with type 2 diabetes

GLP-1 (Glucagon-like peptide-1) plays a crucial role in managing blood sugar levels, reducing appetite, and supporting weight loss by influencing insulin and glucagon production.

Semaglutide notably enhanced the expression of occludin, claudin, and ZO-1, supporting strengthened intestinal barrier integrity, and restored HO-1 expression, indicating improved antioxidant defenses

By 2030, the global prevalence of obesity is expected to reach one billion

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GLP-1RA are guideline-endorsed for patients with T2DM and high CV/renal risk irrespective of HbA1c
