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Since the introduction of GLP-1s, roughly 12% of U.S

[DOI] [PMC free article] [PubMed] [Google Scholar] 337.Liu, L

A large cross-sectional analysis demonstrated impaired semen quality among men with metabolic syndrome, characterised by reduced normal morphology and sperm progressive motility

Pregnancy itself carries distinct risks during rapid weight loss from GLP-1 therapy

Nevertheless, studies have shown significant increases in GLP-1 levels following additional glutamine administration in diabetes mellitus [26, 27, 42]

Additionally, GLP-1 receptor agonists may directly reduce gallbladder emptying and motility, potentially contributing to bile stasis and gallstone formation independently of weight loss effects