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This insight helps your provider select semaglutide, tirzepatide, or a dual-compound formula most likely to work for your biology, maximizing results when combined with metformin

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Postoperative recovery : Do not resume semaglutide if you are experiencing ongoing postoperative nausea, vomiting, inability to maintain adequate oral intake, or any surgical complications

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At standard therapeutic doses, tirzepatide generally produces greater weight loss than semaglutide in head-to-head comparisons
Combining GLP-1 with estrogen into a stable conjugate that stimulates all GLP-1R-expressing cells but only those estrogen receptor-expressing cells that contain GLP-1R leads to better glycemic control and synergistic weight loss, as well as a reduction in food reward, the latter 2 mediated by the CNS (42, 43)
