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Of course I always try to find a juicy topic for member posts but what am I, magic

Heart rate increases have been noted in some tirzepatide trials, though clinical significance remains under investigation

In people, small trials and observational work show signals

This titration schedule helps minimise common gastrointestinal side effects such as nausea, vomiting, diarrhoea, and constipation, which affect a significant proportion of users, particularly during the initial weeks of treatment

Adverse events leading to discontinuation occurred in 47.1% of participants without cirrhosis, 18.8% with Child-Pugh A, and 25.0% with Child-Pugh B

This means it mimics a natural hormone called glucagon-like peptide-1 (GLP-1)