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doi: 10.1002/hep.29367 184 BramanteCTignanelliCJDuttaNJonesETamarizLClarkJMet al

265 SIRT5 regulates the NAD + -dependent elimination of the succinyl, glutaryl, or malonyl groups from lysine residues and, in contrast, is an inefficient deacetylase

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The trial duration of the trials ranged from 26 weeks to 78 weeks, which may be suitable for the assessment of outcomes, but is limited in the applicability to long-term outcomes or sustainability of treatment effect for a chronic disease

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