retatrutide and cholesterol Retatrutide: A Promising Option for Non-Diabetic Weight Loss in Clinical Trials Retatrutide and Heart Issues: Cardiovascular

, Holland, R

Despite their benefits, weight gain, diabetes, metabolic syndrome, and cardiovascular disease are common side effects of this type of drugs, and insulin resistance that may be induced because of their use has been related to changes in DNA methylation, particularly with hypomethylation in fatty acyl CoA reductase 2 [246]

Even though it can be taken under control at home with a sweet snack or special glucose pills, its still better for a doctor to be aware and give recommendations according to a patients individual case

doi: 10.1111/dom.12854

These were trial instructions only, not approved UK patient instructions

Most GLP-1R agonists have gastrointestinal side effects, including nausea, vomiting, diarrhea and constipation, which may be more pronounced in elderly patients with AD and affect treatment compliance