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doi: 10.1001/jama.2017.13276 [DOI] [PubMed] [Google Scholar] 11.Pi-Sunyer X, Astrup A, Fujioka K, et al
Approximately 70% of patients report experiencing food indifference by week 5

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The primary cause is the musculoskeletal adjustment to changing body weight, though inflammation from dehydration and nutrient deficiencies can amplify the sensation

Descriptive analysis of reported adverse events associated with anti-obesity medications using FDA Adverse Event Reporting System (FAERS) databases 2013-2020

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