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Apply gentle pressure with a cotton ball if needed

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These metabolites interact with L-cells in your intestinal lining, which are the cells responsible for producing GLP-1

Medication interactions : Certain medications can interfere with weight loss efforts, including some antidepressants (particularly paroxetine, mirtazapine), antipsychotics (especially olanzapine, quetiapine), mood stabilizers (valproate), antiepileptics (gabapentin, pregabalin), corticosteroids, beta-blockers, and diabetes medications (insulin, sulfonylureas)

N Engl J Med 361:4051