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Semaglutide can affect the absorption of certain oral medications due to its influence on gastric emptying, which may require adjustments in your medication regimen
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Theres also the requirement that a GLP-1 oral medication be taken on an empty stomach

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The clearest evidence comes from SURMOUNT-4, where adults who had lost an average of 20.9% on Mounjaro over 36 weeks were then either continued on the drug or switched to placebo for another year
