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Retatrutide, in early data, outperforms tirzepatide suggesting incremental receptor targeting translates to incremental efficacy

This changes the charge and shape of the peptide, reducing its ability to bind to GIP and GLP-1 receptors effectively

Brand-name list prices run roughly $1,000 to $1,350 per month for both Wegovy and Zepbound, though Eli Lilly's LillyDirect direct-pay vials for Zepbound have brought entry doses closer to $349 to $499 per month

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Safety profile of bimagrumab: RESILIENT trial extension