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Patients on GLP-1 medications should hold daily doses on the day of the procedure and weekly doses seven days prior to surgery

In this scenario, preventing excess glucagon secretion helps lower blood sugar levels

If you suspect you are experiencing side effects from your medication, you can report these through the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk or via the Yellow Card app)
The finding on suicidal ideation is noteworthy, as this was previously a concern following reports of possible cases of self-injury and suicidal thoughts among Icelandic people using GLP-1 receptor agonists.57 These reports resulted in a 2023 European Medicines Agency review, which found no evidence of a causal link

Co-infusion of GLP-1 and glucagon to human subjects resulted in decreased food intake, likely secondary to GLP-1 action, and increased energy expenditure, suggested to be driven by glucagon action [783,785]

Importantly, GLP-1(736) treatment did not affect body weight, systolic blood pressure, or plasma concentrations of total cholesterol, HDL-cholesterol, and triacylglycerol (1)
