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However, the role of GLP-1R in the pathological process of OA is unclear
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Serious adverse events reported in temporal association with GLP-1 RA exposure included anaphylaxis with bronchospasm (n=4 cases), acute eosinophilic pneumonia (n=1), perioperative aspiration pneumonitis or pneumonia (multiple perioperative cases across two cohort studies and one case series), acute respiratory distress syndrome (ARDS

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In those years, Wegovy and Mounjaro, respectively, were the highest-volume and highest-utilization drivers of this overall trend.
