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Potential neural mechanisms for effects of GLP-1RAs on nicotine reward are reviewed, and priorities for future clinical and translational studies are discussed

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A stratified next-generation trial could test whether semaglutide works in the right patients even at the same 14 mg dose that failed in an unselected population

Lifestyle and individual factors also play a role.

For many people, GLP-1 weight loss medications have seemed like a breakthrough in the fight against obesity