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DOI: 10.1056/NEJMoa2403347 11

They focused their analysis only on records that listed GLP-1 RA as monotherapy and reported important medical events, and included 16,350 reports

These immunomodulatory effects complement their metabolic actions, contributing to improved liver outcomes and systemic benefits

Conversations Spiked Amid Speculation Linking GLP-1s and Neurodegenerative Disease Treatment Parkinsons got the biggest spike across all conditions: +2,116% spike following NEJM research suggesting GLP-1s might slow Parkinsons progression

and to reduce/stop if uncontrolled hyperkalemia or to control uremic symptoms when GFR 30 ml/min per 1.73 m2 and subsequently decline to an eGFR 30 ml/min/1.73m2