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A new animal study raises important questions about a little-known ingredient used in oral weight-loss medications

Unlike the current widely used medications such as Ozempic and Mounjaro that target the GLP-1 pathway alone, retatrutide, known as a GLP-3, targets three pathways related to metabolism: GIP, GLP-1, and glucagon

Weight-loss drugs are changing how doctors treat obesity, but in South Africa the cost of approved medicines and the hype around new injections are fuelling a risky illegal market

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and Canada say theyve seen growing numbers of patients on the weight-loss drugs who inhaled food and liquid into their lungs while sedated because their stomachs were still full

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