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Cardiovascular Effects Dose-dependent increases in heart rate were observed with retatrutide: Heart rate increases peaked at approximately 24 weeks Gradually declined thereafter while remaining elevated above baseline This pattern is similar to that observed with other GLP-1 receptor agonists[4] The clinical significance of these heart rate changes requires further evaluation in larger and longer-term studies

Starting at 241 lb, she lost 90 lb (over 30% of her body weight) over 65 weeks without side effects

The incretin hormone glucagon-like peptide 1 (GLP-1) has been implicated in the gutrenal axis and incretin-based therapies might reduce the burden of diabetic kidney disease

Yeast infections are a reported side effect in some people taking semaglutide and other GLP-1 receptor agonists

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Ozempic doesnt directly affect penis size, but losing weight can sometimes make the penis appear larger