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In the future, multitargeted drugs, novel delivery technologies, and individualized treatments may propel them to become breakthrough therapies for a wider range of diseases
One-third of the participants lost at least 20% of their starting weight

Clinical Case: In a Phase II clinical trial, the combination therapy group showed a 40% higher improvement rate in depressive symptoms, a 20% reduction in cortisol levels compared to monotherapy, and more significant HPA axis functional recovery
doi: 10.2337/diabetes.53.1.5 49 WangXZhouJDoyleMEEganJM