glp 1 iih Recurrent Idiopathic Intracranial Hypertension–Related Papilledema After Abrupt Discontinuation of Semaglutide: JNO Article: https://bit.ly/JNO_recurr_IIH_GLP1RA #brain #eye #vision #research #Neurology #NeuroOphth #Ophthalmology #Medicine #Papilledema The effect of glucagon-like peptide-1

In a systematic review of 55 double-blinded, placebo-controlled randomized clinical trials, GLP-1RA treatment was associated with an increased risk of cholelithiasis compared with placebo (RR 1.46, 95% CI 1.091.97) but not cholecystitis, cholangitis, or pancreatitis (63)

BMC Med Res Methodol 2014

In the future, physicians should pay attention to the relationship between GLP-1 RA use and the risk of respiratory diseases and evaluate the efficacy of GLP-1RAs in the primary and secondary prevention of respiratory diseases

Safer interim approaches include dietary modification, structured physical activity, behavioral counseling, and close metabolic monitoring

N Engl J Med 385(10):896907 Gofron KK, Wasilewski A, Magorzewicz S (2025) Effects of GLP-1 analogues and agonists on the gut microbiota: a systematic review

Hypoglycemia (low blood sugar): More common in people taking diabetes medications concurrently