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doi: 10.1677/joe.0.1160357

In support of ghrelins proposed actions through VANs, ghrelin receptors are expressed on VANs, and subdiaphragmatic or gastric vagotomy abolishes increased food intake following peripherally administered ghrelin (1.5 nmol) 220

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Additionally, GLP-1 therapy improves insulin sensitivity and reduces inflammation markers in some patients, which may indirectly support fibromyalgia management since insulin dysregulation and inflammatory pathways are implicated in fibromyalgia pathogenesis

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