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The consequences are severe: prolonged nausea lasting days instead of hours, vomiting that leads to dehydration, severe gastrointestinal distress , and in serious cases, acute pancreatitis requiring hospitalization

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By incorporating estrous monitoring into current pre-clinical biomedical research, experimenters can assess differential effects of drugs and doses across estrous phases, which will be critical for understanding how drugs interact with endogenous fluctuations in hormonal state 72

Phase 3 trials (TRIUMPH programme) are ongoing