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These cytokines activate the nuclear factor kappa-B (NF-B) signaling pathway,inducing the upregulation of apoptotic proteins and matrix-degrading enzymes, such as metalloproteinases (MMPs), which irreversibly degrade the extracellular matrix (ECM) 6,7
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Moreover, the American Heart Association (AHA) 23 recommends that neurologists use GLP-1RAs as part of their stroke prevention strategies for patients with type 2 diabetes at high risk of stroke
The enteric nervous system and neurogastroenterology
Biomed Pharmacother 2019
Your Questions About Hydration on GLP-1 Medications, Answered Why do GLP-1 medications make it hard to stay hydrated
