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Research examining the mechanism of action of GLP-1RA therapy for weight loss shows that the drug is linked to decreased appetite and hunger, decreased preference for foods high in energy, altered food reward pathways, decreased food cravings, and improved eating control

Among them, GLP-1 and GIP (gastric inhibitory polypeptide) are known as incretins, gut-derived hormones that enhance glucose-dependent insulin secretion, playing a pivotal role in maintaining glucose homeostasis and serve as important therapeutic targets for type 2 diabetes and obesity

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Efficacy of GLP-1 RA Approved for Weight Management in Patients With or Without Diabetes: A Narrative Review

Microdosing may be done to reduce the risk of side effects, most notably gastrointestinal side effects such as nausea and constipation, says Dr

The 3 s standard for LOD was employed [41]