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Second, alcohol can lower blood sugar, and combining alcohol with the blood-sugar-lowering effects of tirzepatide, especially shortly after injection, increases the risk of hypoglycemia in susceptible individuals

So, what does a strong case for medical necessity look like

Management: Use cautiously, especially in patients with cardiovascular conditions

You worked hard, your appetite changed, your habits improved, and the number on the scale finally moved where you wanted it to go

Currently, two ongoing clinical trials are investigating the role of GLP-1 RAs in IBD management, that would lead to further knowledge: a French study (ID NCT05196958) evaluating the safety and efficacy of GLP-1 RAs in treatment of DM2 in overweight IBD patients (115), and an American study (ID NCT06774079) comparing the efficacy of GLP-1 RAs tirzepatide versus diet in CD patients (116)