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Aurora A degradation by HSP90 interactome-mediating PROTACs in A549 and paclitaxel-resistant A549 cells

ASN Neuro 4:e00086

[DOI] [PubMed] [Google Scholar] 106.Hossain M.I., Nahar B., Hamadani J.D., Ahmed T., Roy A.K., Brown K.H

2011 Jan;8(1):1014

However, the chemical properties of kaempferol have a dual role: both scavenging free radicals and exerting antioxidant effects through the donation of hydrogen atoms, but under specific conditions, the intermediate products (phenol-oxygen radicals) produced react with oxygen to produce ROS with pro-oxidant effects

240 Furthermore, the KD could enhance the efficacy of phosphatidylinositol 3 kinase (PI3K) inhibitors and overcome drug resistance, which was confirmed in different mouse cancer models, including pancreatic, bladder, endometrial, and breast cancer, as well as in acute myeloid leukemia