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In contrast, PWA mice display overt metabolic perturbations, including overweight and impaired glucose homeostasis 46 , and may mimic the canonical human phenotype A of PCOS linked to hyperandrogenism, anovulatory cycles, and polycystic ovarian morphology 45

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Engages Gs / adenylyl-cyclase / cAMP signaling at each of the three receptors in receptor-expressing cell models

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