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Description

GLP-1 may activate autonomic control sites in the rat brain, including medullary catecholamine neurons providing input to sympathetic preganglionic neurons, 38 and central GLP-1 receptor stimulation was shown to increase blood pressure and heart rate in rodents

These positive effects on glucose homeostasis coupled with the achievement of weight loss manage to reduce hepatic inflammation and steatosis and to improve liver function tests

Additionally, these investments position us to be a leader in providing access to high-quality treatment to millions of more Americans as more brand name GLP-1 medications go generic in the coming years

doi: 10.1016/j.neures.2006.04.008 [DOI] [PubMed] [Google Scholar] 73

What you're not paying for: the FDA premarket review of the finished preparation, the brand-name pharmaceutical manufacturer's R&D cost recovery, or the standardized delivery device (compounded semaglutide typically comes in multi-dose vials, not the pre-filled auto-injector pen you'd get with Wegovy)