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These differences in licking responses are associated to altered protein expression for a salt-sensitive subunit in GHSR KO mice [118] and fatty acid receptors in GOAT null mice [119], thus further highlighting the contribution of ghrelin signaling to salty and fatty taste perception

2013;36(Suppl

Mechanistic candidates supported by recent preclinical and clinical studies include enhanced hippocampal neurogenesis, upregulation of neurotrophic signaling pathways (e.g., brain-derived neurotrophic factor (BDNF)), synaptic remodeling, and neural circuit changes that alter emotional bias processing

Campos AC, Fogaa MV, Sonego AB, et al