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A newer drug of this class is semaglutide (sold under the brand name Wegovy), which was approved in 2021 and was found, on average, to reduce weight by 15% in one clinical trial where people took the drug for 68 weeks

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Jul 2009;11(7):665679

Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

12 Of particular interest, a 20-week research trial involving nondiabetic patients with a mean body mass index of 30 to 40 kg/m 2 at baseline compared the weight loss effects of liraglutide versus orlistat 120 mg three times daily or placebo