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These fibres resist digestion in the small intestine and reach the colon, where they are fermented by beneficial bacteria to produce SCFAs that stimulate GLP-1 release

The exendin-4 treatment has been shown to reduce cocaine self-administration, suggesting that the GLP-1 system may be a novel target of drug addiction (Sorensen et al., 2015)

Thats the biggest source by far, and the most fixable: put the placebo bar next to the drug bar and the fear usually lets go

Those patients will continue to access the drug through traditional coverage

Luminal glucagon-like peptide-1(7-36) amide-releasing factors in the isolated vascularly perfused rat colon

PMID 29439603