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None of these effects require a functioning beta cell which is exactly why researchers started exploring them in T1D
doi: 10.1517/17460441.2014.942638 67 HorowitzMRaynerCKJonesKL

Both Quiescent and Activated PSCs from Normal Rat Expressed the GLP-1R In Vitro and the Expression is Increased in Activated PSCs To further investigate the expression of GLP-1R in normal pancreas and the result of its activation, we studied PSCs isolated from normal pancreas in both a quiescent phase (first passage: 1 day

Accessed 08 Oct 2020
Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women

Many patients stay on a reduced insulin dose rather than stopping entirely
