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That's not a minor nuance - it's the central organizing principle of contemporary HRT guidance

Ann Surg (2009) 250(2):23441.10.1097/SLA.0b013e3181ae32e3 26 LeeWJChongKSerKHLeeYCChenSCChenJCet alGastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial

Accessed December 18, 2024

As addiction progresses, wanting increasingly dominates and becomes dissociated from liking.148 The dark side hypothesis of addiction suggests that impulsivity, compulsivity, and negative urgency emerge from stress experienced during withdrawal or the negative affective phase, potentially persisting months post-withdrawal

Ghrelin directly stimulates glucagon secretion from pancreatic alpha-cells
