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GLP-1RA can also affect the process of skin aging through interaction with advanced glycation end products (AGEs) and RAGE (receptors of AGEs) activation

Rapid weight loss with GLP1 receptor agonists can come at the cost of skeletal muscle, potentially undermining metabolic and functional outcomes

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In patients with diabetes mellitus not achieving targets on lifestyle measures, pharmacologic therapy should be considered

GLP-1 receptor agonists represent one of the most studied medication classes in modern medicine, with over a decade of clinical trial data supporting their effectiveness for sustainable weight loss and improved metabolic markers