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Key Takeaways: Benefits: Lower risk of major cardiovascular events (up to 40% in some studies), improved blood sugar, and weight loss

In the actual universe that we inhabit, the people who most need semaglutide often struggle to get it, and its arrival seems to have prompted less a public consideration of what it means to be fat than a renewed fixation on being thin

Still, the agency said in October that it had received multiple reports of adverse events, some requiring hospitalization, that may be related to dosing errors associated with compounded injectable semaglutide products. The FDA has also warned that some compounders may be selling salt forms of semaglutide, which contain different active ingredients, and that counterfeit forms of Ozempic are being sold

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Thyroid safety is particularly important in adolescents

Future research should track whether the rate of poison control calls stabilizes, decreases, or continues to rise as Medicare coverage expands the patient base