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See the Jastreboff 2022 tirzepatide study on PubMed for full details

CONTRAVE (naltrexone HCl and bupropion HCl) extended-release tablets are intended for oral use only

Insurance coverage supports nearly 50% of patients, improving access to therapy

About 23% of patients in clinical trials reported symptoms including burning, tingling, skin pain, or sensitive skin

Left untreated, complications of constipation may lead to hemorrhoids, anal fissures, trouble controlling bowel movements (fecal incontinence), and/or intestinal damage
