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The Peptide group maintained sustained Exe4 concentration for 8 weeks, but it became undetectable after pump removal

GLP1 receptor agonists, given systemically, mimic the action of postprandial endogenous gutderived GLP1 and additionally access GLP1 receptors located in the part of the CNS that is not protected by the BBB

Phase: Phase 2 (Breakthrough Therapy Designation, moving to Phase 3) NCT: NCT05385783 Mechanism: Deuterated psilocybin analog (psychedelic-derived, 5-HT2A receptor agonist) Side Effect Comparison: Transient mild-moderate headache, nausea, and anxiety during dosing session

Originally, they were diabetes medications to improve blood glucose control

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