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Less common adverse effects were a temporary increase in alanine aminotransferase (ALT) levels, increased heart rate, and skin hyperesthesia [39]

To assess adiposity, the gonadal adipose tissue was measured at the end of the study (Fig

Questions remain about the safety of these drugs with regard to the risk of pancreatitis and the development of MTC in patients receiving liraglutide

Moreover, expression of the pro-apoptotic protein Bax was reduced while Bcl2 expression increased, revealing that GLP-1RA can inhibit the apoptotic pathway

(Copenh) 129 , 393398 (1993)

3 illustrates GLP-1R-mediated intracellular signaling