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This creates a specific risk: muscle loss

Peak days favor lighter meals

it may be useful as a screening method [136]

These delays highlight the structural barriers that can slow adoption in populations with higher rates of comorbidities
For astrocytes, GLP-1R activation prevents conversion to neurotoxic A1 phenotypes by interrupting microglia-derived IL-1/TNF-/C1q signaling [24,47,48], thereby promoting amyloid- clearance in Alzheimer's disease models [48] and pathogenic -synuclein in PD models [47]