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This creates a specific risk: muscle loss

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it may be useful as a screening method [136]

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These delays highlight the structural barriers that can slow adoption in populations with higher rates of comorbidities

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For astrocytes, GLP-1R activation prevents conversion to neurotoxic A1 phenotypes by interrupting microglia-derived IL-1/TNF-/C1q signaling [24,47,48], thereby promoting amyloid- clearance in Alzheimer's disease models [48] and pathogenic -synuclein in PD models [47]

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