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GLP-1 agonists slow stomach emptying and can worsen diarrhea in this population by allowing more time for abnormal bile acid handling in the small intestine

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Depression is not a common side effect in clinical trials, but individual reports exist

A Sanofi spokesperson said the company was aware of illegally mislabeled insulin glulisine pens being passed off as semaglutide, and has been working with partners to protect patients, but declined to comment on whether the company has since tried to distinguish its product from Novo's

This is still enormously useful because the shape of the curve, the peaks, troughs, and accumulation pattern, reflects real pharmacokinetic behavior