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Head-to-Head Efficacy: Tirzepatide Wins 22% vs 15% Weight Loss The most robust head-to-head comparison comes from the SURPASS-2 trial, a 40-week, phase 3 study of 1,879 adults with type 2 diabetes, published in the N Engl J Med
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They showed a mean weight loss of 5.8-7.0 kg after 6 months
The duration of the reaction may range from 10 to 30 minutes, preferably for the period of 15 to 20 minutes
