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10.1186/s12951-023-02173-x

(13), and others likely reflect differences in experimental paradigms, including the specific GLP-1R agonist used (short acting versus long acting, small molecule versus large molecule, etc.), the route of administration (i.p., s.c., or i.v.), dose, species studied, acute versus chronic analysis, and intrinsic shortcomings in the specific model systems used, such as lack of complete tissue specificity with Cre drivers, incomplete knockdowns, and potential developmental compensation when using constitutively active versus tamoxifen-inducible Cre systems

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No treatment-related deaths were reported in either group

Understanding proper storage is essential for patients to ensure optimal therapeutic outcomes

Cons As with any prescription medication, there are also pros and cons to consider before starting use